How many people call poison control each year? On average, poison control centers receive about 2.2 million calls each year from people seeking medical help for poisoning. Poisoning is the leading cause of unintentional death. (2016) By ProMatcher Staff Updated: 08/08/2016 Next Question Source: National Safety Council Next Question Find Local Pros Free Actuaries Cost Estimates Related Questions How many injuries involve vacuum cleaners? How Many Forklift Injuries Occur Each Year? How many people are killed by wood chippers? How many flooring-related injuries occur each year? How many home fires occur each year?